0 votes
in Medical Academics Questions by
related to an answer for: how cirrhosis causes breast atrophy?

Please log in or register to answer this question.

1 Answer

0 votes
by Doctor of Medicine (5.6k points)
**Gynecomastia in men**: In CLD, there is defective metabolism of androstenedione, thereby shunting the estrogen precursors and increasing plasma level of estradiol. Additionaly, Spironolactone may be used in CLD, which is a testosterone inhibitor.

**Breast atrophy in women:** Serum hormone binding globulin (SHBG) is decreased in liver cirrhosis leading to increased bioavailable androgens in females. This can lead to hirsuitism and defeminization. Breast atrophy is one of the early manifestations in female due to this reason.

Related questions

+2 votes
1 answer 11.1k views
+2 votes
1 answer 350 views
0 votes
0 answers 453 views
+1 vote
2 answers 553 views
Medchrome Answers is a free Question & Answer platform where members can ask and answer medical questions and health queries.

318 questions

356 answers


23 users