What is the mechanism of splitting of second heart sound during inspiration?

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During inspiration, there is increased venous return to the right side of heart and also there is pooling of blood in the pulmonary veins due to its elasticity. This leads to early closure of aortic valce relative to the pulmonary valve resulting in splitting of the 2nd heart sound.

answered Jun 12, 2015 by Sulabh Shrestha Doctor of Medicine (5,553 points)