Why proton pump inhibitors are taken before meal?

Question

Recently, in pharmacology test, they asked this question and I couldn't answer. What is the reason PPIs like omeprazole are taken before meal?

Answer 1

bcz wen dey r tkn b4 meals .. it is at d peak levels in d body ..and cn effectively supress d acid production vch mostly occur aftr meals ... if v tk it aftr meals so conc. is nt appropriate to match d acid neutralisation bcz acid prodn vll b more aftr meals

Comments

B/c acid production will be greater aftet meal.

Answer 2

Because PPIs are used to suppress acid secretion so they are only useful if they are taken before the meal.

After the meal, acid has already bean released so it is almost useless to use them after PPIs.