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coronary steal. why GTN does not dilate resistance vessels?

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asked Feb 6, 2014 in Medical Academics Questions by bk

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2 Answers

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The answer has already been discussed here: http://answers.medchrome.com/1001/what-is-coronary-steal-phenomenon

answered Mar 7, 2014 by admin Doctor of Medicine (9,784 points)
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There is evidence from Harrison and Bates (1993) (Circulation vol 87, p 1461) that GTN dilates larger coronary arteries better than smaller ones. This would have little effect on the overall resistance of, and flow through, through normal coronary arteries (since resistance mainly resides in the arterioles which are not dilated), but could increase flow through coronary collaterals, thereby improving flow in stenosed coronary arteries.

answered Mar 9 by anonymous
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