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What is mobius syndrome?
Inheritence and clinical features?

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by Doctor of Medicine (5.6k points)
Moebius syndrome is a birth defect caused by the absence or underdevelopment of the 6th and 7th cranial nerves. Many of the other cranial nerves may also be affected, including the 3rd, 5th, 8th, 9th, 11th and 12th.

![enter image description here][1]


 - Inability to suck
 - feeding, swallowing, and choking problems
 - excessive drooling
 - crossed eyes
 - lack of facial expression; inability to smile
 - motor delays
 - high or cleft palate
 - hearing problems and speech difficulties.
 - unable to move their eyes back and forth.

Associations: Club foot, Brachial abnormalities, Autism

Inheritance: Most cases of Moebius syndrome are sporadic, which means they occur in people with no history of the disorder in their family. A small percentage of all cases have been reported to run in families; however, the condition does not have a single clear pattern of inheritance.

  [1]: http://www.hxbenefit.com/wp-content/uploads/2013/01/Moebius-Syndrome-Image.jpg

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