What is Parinaud Syndrome?

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What is Parinaud Syndrome?
When does it occur?
Any treatment?

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1 Answer


Parinaud syndrome (also known as the dorsal midbrain syndrome) is a supranuclear vertical gaze disturbance caused by compression of the tectal plate. This is most frequently due to a posterior commisure or pineal region mass (typically solid tumours rather than pineal cysts).

It is characterised by:

  • a deficiency in upward-gaze
  • pupillary light-near dissociation (pupils respond to near stimuli but not light)
  • convergence-retraction nystagmus


Treatment is primarily directed towards the etiology of dorsal midbrain syndrome. A thorough work up including neuroimaging is essential to rule out the various causes of dorsal midbrain syndrome.

answered Jul 12, 2014 by Sulabh Shrestha Doctor of Medicine (5,553 points)